61476-45-7

61476-45-7 structure

Name: (1S)-Calcitriol
Chemical Name: (1S)-Calcitriol
CAS Number: 61476-45-7
Molecular Formula: C₂₇H₄₄O₃
Molecular Weight: 416.64
Catalog: Research Areas Others
Create Date: 2021-09-11 14:39:09
Modify Date: 2024-01-11 16:09:38
(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1].

Name	(1S)-Calcitriol

Description	(1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3). (1S)-Calcitriol exhibits potent vitamin D receptor (VDR)-mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	3‐epi‐Calcitroic acid is an end product of (1S)-Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3; 3‐epi‐1a,25(OH)2D3) metabolism by rat CYP24A1[1].
References	[1]. Steve Y Rhieu, et al. Metabolic stability of 3-epi-1α,25-dihydroxyvitamin D3 over 1 α 25-dihydroxyvitamin D3: metabolism and molecular docking studies using rat CYP24A1. J Cell Biochem. 2013 Oct;114(10):2293-305.

Molecular Formula	C₂₇H₄₄O₃
Molecular Weight	416.64