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1087243-14-8

1087243-14-8 structure
1087243-14-8 structure
  • Name: GRL-0496
  • Chemical Name: GRL-0496
  • CAS Number: 1087243-14-8
  • Molecular Formula: C14H9ClN2O2
  • Molecular Weight: 272.69
  • Catalog: Signaling Pathways Anti-infection SARS-CoV
  • Create Date: 2021-09-11 19:50:48
  • Modify Date: 2024-01-05 10:37:56
  • GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM[1].
Name GRL-0496
Description GRL-0496 is a potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL-0496 shows SARS-CoV antiviral activity, with an EC50 of 6.9 μM[1].
Related Catalog
Target

IC50: 30 nM (SARS-CoV 3CLpro)[1]

In Vitro GRL-0496 shows the best SARS-CoV antiviral activity, with an EC EC50 of 6.9 μM[1].
References

[1]. Ghosh AK, et, al. Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5684-8.
Molecular Formula C14H9ClN2O2
Molecular Weight 272.69

Chemsrc provides CAS#:1087243-14-8 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 1087243-14-8 | Chemsrc address: https://www.chemsrc.com/en/baike/1681313.html

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