1122579-42-3

1122579-42-3 structure

Name: PI-55
Chemical Name: PI-55
CAS Number: 1122579-42-3
Molecular Formula: C₁₃H₁₃N₅O
Molecular Weight: 255.28
Catalog: Research Areas Infection
Create Date: 2021-09-14 07:16:24
Modify Date: 2024-01-05 01:59:01
PI-55 is a specific cytokinin receptor inhibitor. PI-55 is structurally related to 6-benzylaminopurine (BAP) and was shown to inhibit competitively BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3. PI-55 inhibits cytokinins induced haustorium formation and increased parasite aggressiveness[1].

Name	PI-55
Synonyms	MFCD34165679

Description	PI-55 is a specific cytokinin receptor inhibitor. PI-55 is structurally related to 6-benzylaminopurine (BAP) and was shown to inhibit competitively BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3. PI-55 inhibits cytokinins induced haustorium formation and increased parasite aggressiveness[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
Target	Cytokinin receptor[1]. Parasiter[1]
In Vitro	PI-55 at high concentrations (10 μM and 100 μM), which causes an incomplete blocking of early haustorial structure development, especially when cytokinin activity promotes it. PI-55 treatment also reduces the overall aggressiveness of P. ramosa when applied with BAP in comparison with BAP alone, suggesting that the signaling pathway leading to early haustorial structure formation involves histidine kinase receptors homologous to CRE1/AHK4 and AHK3[1].
References	[1]. Goyet V, et al. Haustorium initiation in the obligate parasitic plant Phelipanche ramosa involves a host-exudated cytokinin signal. J Exp Bot. 2017;68(20):5539-5552.

Molecular Formula	C₁₃H₁₃N₅O
Molecular Weight	255.28

Hazard Codes	Xi