DC Chemicals Limited
China
Product Name: (S,R,S)-AHPC-C2-NH2
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

2241643-69-4

2241643-69-4 structure

2241643-69-4 structure

Name: (S,R,S)-AHPC-C2-NH2
Chemical Name: (S,R,S)-AHPC-C2-NH2
CAS Number: 2241643-69-4
Molecular Formula: C₂₅H₃₅N₅O₄S
Molecular Weight: 501.64
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2021-09-09 22:53:20
Modify Date: 2024-01-05 17:10:47
(S,R,S)-AHPC-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology[1].

Name	(S,R,S)-AHPC-C2-NH2

Description	(S,R,S)-AHPC-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	VHL
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References	[1]. Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019;17:160-176. Published 2019 Jan 25. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Molecular Formula	C₂₅H₃₅N₅O₄S
Molecular Weight	501.64

Hazard Codes	Xi