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1189648-08-5

1189648-08-5 structure
1189648-08-5 structure
  • Name: Melitracen-d6 hydrochloride
  • Chemical Name: Melitracen-d6 hydrochloride
  • CAS Number: 1189648-08-5
  • Molecular Formula: C21H20D6ClN
  • Molecular Weight: 333.93
  • Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
  • Create Date: 2021-10-07 18:14:55
  • Modify Date: 2024-01-09 10:03:24
  • Melitracen-d6 hydrochloride is the deuterium labeled Melitracen hydrochloride. Melitracen hydrochloride is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5-HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space[1][2].
Name Melitracen-d6 hydrochloride
Description Melitracen-d6 hydrochloride is the deuterium labeled Melitracen hydrochloride. Melitracen hydrochloride is an orally active biphasic antidepressant and antianxiety agent. Melitracen hydrochloride can inhibit the uptake of Norepinephrine and 5-HT (serotonin) through the presynaptic membrane inducing the increase of monoamine transmitters in synaptic space[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Xiaoqian Zhou , et al. The Efficacy of Flupentixol-Melitracen in the Adjuvant Therapy of Ulcerative Colitis in the Chinese Population: A Meta-Analysis. Gastroenterol Res Pract. 2019 Feb 28;2019:3480732.

[3]. K Shimamoto, et al. Myriatic Effect of 9-(gamma-dimethylamino-propylidene)-10, 10-diemthyl-9, 10-dihydroanthracene Hydrochloride (Melitracen) in Mice and Rats. Acta Sch Med Univ Kioto. 1967 Jul;40(1):38-47.
Molecular Formula C21H20D6ClN
Molecular Weight 333.93

Chemsrc provides CAS#:1189648-08-5 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 1189648-08-5 | Chemsrc address: https://www.chemsrc.com/en/baike/1682077.html

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