126320-79-4

126320-79-4 structure
126320-79-4 structure
  • Name: Suprofen-d3
  • Chemical Name: Suprofen-d3
  • CAS Number: 126320-79-4
  • Molecular Formula: C14H9D3O3S
  • Molecular Weight: 263.33
  • Catalog: Signaling Pathways Immunology/Inflammation PGE synthase
  • Create Date: 2021-10-19 13:10:27
  • Modify Date: 2024-01-10 09:38:08
  • Suprofen-d3 (TN-762-d3) is the deuterium labeled Suprofen. Suprofen (TN-762) is a non-steroidal anti-inflammatory drug (NSAID)[1][2].

Name Suprofen-d3
Description Suprofen-d3 (TN-762-d3) is the deuterium labeled Suprofen. Suprofen (TN-762) is a non-steroidal anti-inflammatory drug (NSAID)[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Yeadon, A., et al., Suprofen. An overview of long-term safety. Pharmacology, 1983. 27 Suppl 1: p. 87-94.

[3]. Dawood, M.Y. and F.S. Khan-Dawood, Differential suppression of menstrual fluid prostaglandin F2a, prostaglandin E2, 6-keto prostaglandin F1a and thromboxane B2 by suprofen in women with primary dysmenorrhea. Prostaglandins Other Lipid Mediat, 2007. 83(1-2): p. 146-53.

Molecular Formula C14H9D3O3S
Molecular Weight 263.33