Name | Benzamide, N-[2-[(3S)-3-[[cis-4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)- |
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Synonyms |
Benzamide, N-[2-[(3S)-3-[[trans-4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)-
PF-4136309 N-{2-[(3S)-3-({trans-4-Hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl}amino)-1-pyrrolidinyl]-2-oxoethyl}-3-(trifluoromethyl)benzamide MFCD22124474 |
Description | (s)-PF-4136309 is the inactive isomer of PF-4136309 (HY-13245), and can be used as an experimental control. PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2. |
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Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 712.2±60.0 °C at 760 mmHg |
Molecular Formula | C29H31F3N6O3 |
Molecular Weight | 568.59 |
Flash Point | 384.5±32.9 °C |
Exact Mass | 568.240967 |
LogP | 2.10 |
Vapour Pressure | 0.0±2.4 mmHg at 25°C |
Index of Refraction | 1.626 |