2382768-55-8

2382768-55-8 structure
2382768-55-8 structure
  • Name: (32-Carbonyl)-RMC-5552
  • Chemical Name: (32-Carbonyl)-RMC-5552
  • CAS Number: 2382768-55-8
  • Molecular Formula: C93H134N10O24
  • Molecular Weight: 1776.11
  • Catalog: Signaling Pathways PI3K/Akt/mTOR mTOR
  • Create Date: 2021-12-19 22:17:42
  • Modify Date: 2024-01-11 21:39:24
  • (32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC50s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2)[1].

Name (32-Carbonyl)-RMC-5552
Description (32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC50s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2)[1].
Related Catalog
References

[1]. Jennifer PITZEN, et al. C40-, c28-, and c-32-linked rapamycin analogs as mtor inhibitors. WO2019212990A1.

Molecular Formula C93H134N10O24
Molecular Weight 1776.11