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2369979-68-8

2369979-68-8 structure
2369979-68-8 structure
  • Name: JHU 37160
  • Chemical Name: JHU37160
  • CAS Number: 2369979-68-8
  • Molecular Formula: C19H20ClFN4
  • Molecular Weight: 358.8403
  • Create Date: 2022-01-07 10:12:16
  • Modify Date: 2024-07-07 13:04:23
  • JHU37160 is a potent and brain-penetrant DREADD agonist, with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue.

Name JHU37160
Synonyms MFCD20727945
Description JHU37160 is a potent and brain-penetrant DREADD agonist, with EC50s of 18.5 nM and 0.2 nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue.
Molecular Formula C19H20ClFN4
Molecular Weight 358.8403