Shanghai Nianxing Industrial Co., Ltd
China
Product Name: IACS-15414
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Huang

DC Chemicals Limited
China
Product Name: IACS-15414
Price: $1920.0/100mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2411321-29-2

2411321-29-2 structure

2411321-29-2 structure

Name: IACS-15414
Chemical Name: IACS-15414
CAS Number: 2411321-29-2
Molecular Formula: C₂₀H₂₄Cl₂N₄O₂
Molecular Weight: 423.34
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
Create Date: 2022-03-01 08:23:03
Modify Date: 2024-01-10 21:26:35
IACS-15414 is a potent and orally bioavailable SHP2 inhibitor with an IC50 value of 122 nM.

Name	IACS-15414

Description	IACS-15414 is a potent and orally bioavailable SHP2 inhibitor with an IC50 value of 122 nM.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase
References	[1]. Czako B, et al. Discovery of 6-[(3S,4S)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor. J Med Chem. 2021 Oct 28;64(20):15141-15169.

Molecular Formula	C₂₀H₂₄Cl₂N₄O₂
Molecular Weight	423.34