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117405-58-0

117405-58-0 structure
117405-58-0 structure
  • Name: 3FAx-Neu5Ac
  • Chemical Name: P-3FAX-Neu5Ac
  • CAS Number: 117405-58-0
  • Molecular Formula: C22H30FNO14
  • Molecular Weight: 551.47
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2022-04-02 10:40:18
  • Modify Date: 2024-01-12 01:47:53
  • 3FAx-Neu5Ac (compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X on myeloid cells[1].

Name P-3FAX-Neu5Ac
Synonyms 5-(acetylamino)-3,5-dideoxy-3-fluoro-D-erythro-α-L-manno-2-nonulopyranosonic acid methyl ester 2,4,7,8,9-pentaacetate
Methyl (6S)-5-acetamido-2,4-di-O-acetyl-3,5-dideoxy-3-fluoro-6-[(1S,2R)-1,2,3-triacetoxypropyl]-L-tagatopyranosonate
D-erythro-D-gulo-2-Nonulopyranosonic acid, 5-(acetylamino)-3,5-dideoxy-3-fluoro-, methyl ester, 2,4,7,8,9-pentaacetate
Description 3FAx-Neu5Ac (compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X on myeloid cells[1].
Related Catalog
References

[1]. Cory D Rillahan, et al. Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome. Nat Chem Biol. 2012 Jul;8(7):661-8.  

Density 1.4±0.1 g/cm3
Boiling Point 606.3±55.0 °C at 760 mmHg
Molecular Formula C22H30FNO14
Molecular Weight 551.47
Flash Point 320.5±31.5 °C
Exact Mass 551.165039
LogP 1.65
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.493