3FAx-Neu5Ac

Modify Date: 2024-01-12 01:47:53

3FAx-Neu5Ac Structure
3FAx-Neu5Ac structure
Common Name 3FAx-Neu5Ac
CAS Number 117405-58-0 Molecular Weight 551.47
Density 1.4±0.1 g/cm3 Boiling Point 606.3±55.0 °C at 760 mmHg
Molecular Formula C22H30FNO14 Melting Point N/A
MSDS N/A Flash Point 320.5±31.5 °C

 Use of 3FAx-Neu5Ac


3FAx-Neu5Ac (compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X on myeloid cells[1].

 Names

Name P-3FAX-Neu5Ac
Synonym More Synonyms

 3FAx-Neu5Ac Biological Activity

Description 3FAx-Neu5Ac (compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X on myeloid cells[1].
Related Catalog
References

[1]. Cory D Rillahan, et al. Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome. Nat Chem Biol. 2012 Jul;8(7):661-8.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 606.3±55.0 °C at 760 mmHg
Molecular Formula C22H30FNO14
Molecular Weight 551.47
Flash Point 320.5±31.5 °C
Exact Mass 551.165039
LogP 1.65
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.493

 Synonyms

5-(acetylamino)-3,5-dideoxy-3-fluoro-D-erythro-α-L-manno-2-nonulopyranosonic acid methyl ester 2,4,7,8,9-pentaacetate
Methyl (6S)-5-acetamido-2,4-di-O-acetyl-3,5-dideoxy-3-fluoro-6-[(1S,2R)-1,2,3-triacetoxypropyl]-L-tagatopyranosonate
D-erythro-D-gulo-2-Nonulopyranosonic acid, 5-(acetylamino)-3,5-dideoxy-3-fluoro-, methyl ester, 2,4,7,8,9-pentaacetate