1019106-73-0

1019106-73-0 structure

Name: KCa2 channel modulator 1
Chemical Name: KCa2 channel modulator 1
CAS Number: 1019106-73-0
Molecular Formula: C₁₆H₁₅ClFN₅
Molecular Weight: 331.78
Create Date: 2022-06-27 14:10:26
Modify Date: 2024-01-14 18:27:23
KCa2 channel modulator 1 (compound 2o) is a potent subtype-selective positive modulator of KCa2 channel. KCa2 channel modulator 1 potentiates human KCa2.3 channels with an EC50 value of 0.19 μM and 0.99 μM on the rat KCa2.2 channel subtype[1].

Name	KCa2 channel modulator 1

Description	KCa2 channel modulator 1 (compound 2o) is a potent subtype-selective positive modulator of KCa2 channel. KCa2 channel modulator 1 potentiates human KCa2.3 channels with an EC50 value of 0.19 μM and 0.99 μM on the rat KCa2.2 channel subtype[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. El-Sayed NS, et al. Structure-Activity Relationship Study of Subtype-Selective Positive Modulators of KCa2 Channels. J Med Chem. 2022;65(1):303-322.

Molecular Formula	C₁₆H₁₅ClFN₅
Molecular Weight	331.78