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2408406-89-1

2408406-89-1 structure
2408406-89-1 structure
  • Name: P-gp inhibitor 2
  • Chemical Name: P-gp inhibitor 2
  • CAS Number: 2408406-89-1
  • Molecular Formula: C29H26N2O6
  • Molecular Weight: 498.53
  • Create Date: 2022-05-30 01:07:17
  • Modify Date: 2024-01-08 06:28:49
  • P-gp inhibitor 2 is a potent P-gp inhibitor. P-gp inhibitor 2 shows reverse Doxorubicin resistance (IC50=0.22 µM) in P-gp overexpressing human colorectal carcinoma cells (SW600 Ad300)[1].

Name P-gp inhibitor 2
Description P-gp inhibitor 2 is a potent P-gp inhibitor. P-gp inhibitor 2 shows reverse Doxorubicin resistance (IC50=0.22 µM) in P-gp overexpressing human colorectal carcinoma cells (SW600 Ad300)[1].
Related Catalog
In Vitro P-gp inhibitor 2 (compound 2) exhibits no cytotoxicity (IC50>30 µM) toward human carcinoma (SW600) cells[1].
References

[1]. Dewa AA, et al. Neochrysosporazines: Precursor-Directed Biosynthesis Defines a Marine-Derived Fungal Natural Product P-Glycoprotein Inhibitory Pharmacophore. J Med Chem. 2022, 65(3):2610-2622.

Molecular Formula C29H26N2O6
Molecular Weight 498.53