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118063-12-0

118063-12-0 structure
118063-12-0 structure
  • Name: Retinol-d4
  • Chemical Name: Retinol-d4
  • CAS Number: 118063-12-0
  • Molecular Formula: C20H26D4O
  • Molecular Weight: 290.48
  • Create Date: 2022-06-22 09:22:44
  • Modify Date: 2024-01-14 06:20:13
  • Retinol-d4 (Vitamin A1-d4) is the deuterium labeled Vitamin A. Retinol is an endogenous metabolite.

Name Retinol-d4
Description Retinol-d4 (Vitamin A1-d4) is the deuterium labeled Vitamin A. Retinol is an endogenous metabolite.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Zhang M, et al. High-fat diet enhanced retinal dehydrogenase activity, but suppressed retinol dehydrogenase activity in liver of rats. J Pharmacol Sci. 2015 Apr;127(4):430-8.

[3]. Miyazaki H, et al. Retinol status and expression of retinol-related proteins in methionine-choline deficient rats. J Nutr Sci Vitaminol (Tokyo). 2014;60(2):78-85.

Molecular Formula C20H26D4O
Molecular Weight 290.48