212848-81-2

212848-81-2 structure

212848-81-2 structure

Name: Retinol-d8
Chemical Name: Retinol-d8
CAS Number: 212848-81-2
Molecular Formula: C₂₀H₂₂D₈O
Molecular Weight: 294.50
Catalog: Research Areas Metabolic Disease
Create Date: 2022-10-11 18:38:32
Modify Date: 2024-01-11 14:19:06
Retinol-d8 is the deuterium labeled Vitamin A. Retinol is an endogenous metabolite.

Name	Retinol-d8

Description	Retinol-d8 is the deuterium labeled Vitamin A. Retinol is an endogenous metabolite.
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Zhang M, et al. High-fat diet enhanced retinal dehydrogenase activity, but suppressed retinol dehydrogenase activity in liver of rats. J Pharmacol Sci. 2015 Apr;127(4):430-8.;Miyazaki H, et al. Retinol status and expression of retinol-related proteins in

Molecular Formula	C₂₀H₂₂D₈O
Molecular Weight	294.50