2446136-17-8

2446136-17-8 structure
2446136-17-8 structure
  • Name: Aldose reductase-IN-4
  • Chemical Name: Aldose reductase-IN-4
  • CAS Number: 2446136-17-8
  • Molecular Formula: C14H10FNO3S
  • Molecular Weight: 291.30
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Aldose Reductase
  • Create Date: 2022-05-20 23:27:26
  • Modify Date: 2024-01-06 13:43:22
  • Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].

Name Aldose reductase-IN-4
Description Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].
Related Catalog
Target

IC50: 11.70 μM (Aldehyde reductase 1) and 0.98 μM (Aldehyde reductase 2)[1]

References

[1]. Konstantinos Koutsopoulos, et al. Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl-sulfonyl-phenols. Bioorg Med Chem. 2020 Aug 1;28(15):115575.

Molecular Formula C14H10FNO3S
Molecular Weight 291.30