2761577-50-6

2761577-50-6 structure
2761577-50-6 structure
  • Name: Anti-osteoporosis agent-1
  • Chemical Name: Anti-osteoporosis agent-1
  • CAS Number: 2761577-50-6
  • Molecular Formula: C20H19ClN2O2
  • Molecular Weight: 354.83
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2022-07-12 17:45:52
  • Modify Date: 2024-01-10 17:02:59
  • Anti-osteoporosis agent-1 (comp 4aa) is a potent replication protein A (RPA) inhibitor (IC50=18 µM) [1].

Name Anti-osteoporosis agent-1
Description Anti-osteoporosis agent-1 (comp 4aa) is a potent replication protein A (RPA) inhibitor (IC50=18 µM) [1].
Related Catalog
In Vitro Anti-osteoporosis agent-1 is an active molecule which showed effective mineralisation of osteoblast cells and up regulates the osteogenic marker gene such as Bmp-2, Runx-2 and Type-1col at both transcriptional and translational level. Besides exhibiting potential osteogenic activity. In addition, Anti-osteoporosis agent-1 also own significant anti-apoptotic activity at 1 pM &100 pM concentration and increases the osteoblast survival in serum deprived conditions[1].
References

[1]. Kriti Sharma, et al. Pyrazoline analogues: Design, synthesis, and evaluation of anti-osteoporosis activity. Bioorg Med Chem Lett. 2022 Mar 15; 60:128585.

Molecular Formula C20H19ClN2O2
Molecular Weight 354.83