2089130-74-3

2089130-74-3 structure

Name: LEO 134310
Chemical Name: LEO 134310
CAS Number: 2089130-74-3
Molecular Formula: C₃₄H₄₀N₂O₈
Molecular Weight: 604.69
Catalog: Signaling Pathways GPCR/G Protein Glucocorticoid Receptor
Create Date: 2022-06-03 17:30:19
Modify Date: 2024-01-06 08:01:28
LEO 134310 is a selective, non-steroidal glucocorticoid receptor (GR) agonist optimized for topical treatment., LEO 134310 showed high affinity (EC50 of 14 nM) in a GR binding assay. LEO 134310 can be used for skin diseases[1].

Name	LEO 134310

Description	LEO 134310 is a selective, non-steroidal glucocorticoid receptor (GR) agonist optimized for topical treatment., LEO 134310 showed high affinity (EC50 of 14 nM) in a GR binding assay. LEO 134310 can be used for skin diseases[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor
References	[1]. Stefan Eirefelt, et al. Characterization of a novel non-steroidal glucocorticoid receptor agonist optimized for topical treatment. Sci Rep. 2022 Jan 27;12(1):1501.

Molecular Formula	C₃₄H₄₀N₂O₈
Molecular Weight	604.69