2714473-10-4

2714473-10-4 structure
2714473-10-4 structure
  • Name: Miglitol-d4
  • Chemical Name: Miglitol-d4
  • CAS Number: 2714473-10-4
  • Molecular Formula: C8H13D4NO5
  • Molecular Weight: 211.25
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2022-07-12 23:17:27
  • Modify Date: 2024-04-07 12:13:28
  • Miglitol-d4 is deuterium labeled Miglitol.

Name Miglitol-d4
Description Miglitol-d4 is deuterium labeled Miglitol.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Fukaya, N., et al., The alpha-glucosidase inhibitor miglitol delays the development of diabetes and dysfunctional insulin secretion in pancreatic beta-cells in OLETF rats. Eur J Pharmacol, 2009. 624(1-3): p. 51-7.

[3]. Hirata, A., et al., Effect of miglitol, an alpha-glucosidase inhibitor, on atherogenic outcomes in balloon-injured diabetic rats. Horm Metab Res, 2009. 41(3): p. 213-20.

Molecular Formula C8H13D4NO5
Molecular Weight 211.25