2747914-16-3

2747914-16-3 structure

Name: (±)-Darifenacin-d4 hydrobromide
Chemical Name: (±)-Darifenacin-d4 hydrobromide
CAS Number: 2747914-16-3
Molecular Formula: C₂₈H₂₇D₄BrN₂O₂
Molecular Weight: 511.49
Catalog: Signaling Pathways GPCR/G Protein mAChR
Create Date: 2022-07-02 19:15:43
Modify Date: 2024-01-20 11:39:40
(±)-Darifenacin-d4 (hydrobromide) is deuterium labeled (±)-Darifenacin. (±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective M3 muscarinic receptor antagonist[1].

Name	(±)-Darifenacin-d4 hydrobromide

Description	(±)-Darifenacin-d4 (hydrobromide) is deuterium labeled (±)-Darifenacin. (±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective M3 muscarinic receptor antagonist[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Hegde SS, et al. Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo. Br J Pharmacol, 1997, 120(8), 1409-1418.

Molecular Formula	C₂₈H₂₇D₄BrN₂O₂
Molecular Weight	511.49