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1574602-93-9

1574602-93-9 structure
1574602-93-9 structure
  • Name: DC-TEADin1072
  • Chemical Name: DC-TEADin1072
  • CAS Number: 1574602-93-9
  • Molecular Formula: C16H21NO2
  • Molecular Weight: 259.349
  • Create Date: 2022-07-01 17:15:16
  • Modify Date: 2024-04-05 19:01:28
  • DC-TEADin1072 is a novel TEAD1/3 covalent inhibitor with biochemical IC50 values of 0.61 and 0.58 uM against TEAD1 and TEAD3, respectively.TEADin1072 selectively inhibited TEAD1 and TEAD3 palmitoylation while sparing TEAD2 and TEAD4.TEADin1072 demonstrated selective engagement with Cys371 of TEAD3 and Cys359 of TEAD1.
Name DC-TEADin1072
Description DC-TEADin1072 is a novel TEAD1/3 covalent inhibitor with biochemical IC50 values of 0.61 and 0.58 uM against TEAD1 and TEAD3, respectively.TEADin1072 selectively inhibited TEAD1 and TEAD3 palmitoylation while sparing TEAD2 and TEAD4.TEADin1072 demonstrated selective engagement with Cys371 of TEAD3 and Cys359 of TEAD1.
References 1. Tian Lu, et al. Acta Pharm Sin B. 2021 Oct;11(10):3206-3219.
Molecular Formula C16H21NO2
Molecular Weight 259.349

Chemsrc provides CAS#:1574602-93-9 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 1574602-93-9 | Chemsrc address: https://www.chemsrc.com/en/baike/1707664.html

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