2412592-33-5

2412592-33-5 structure

Name: Antimicrobial agent-2
Chemical Name: Antimicrobial agent-2
CAS Number: 2412592-33-5
Molecular Formula: C₁₆H₁₄N₂O₄S
Molecular Weight: 330.36
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK ROS
Create Date: 2022-07-01 17:12:21
Modify Date: 2024-01-03 11:09:55
Antimicrobial agent-2 (compound V-a) is a broad-spectrum antimicrobial agent, possessing inhibitory activity against various Gram-positive and -negative bacteria. Antimicrobial agent-2 has excellent inhibitory effect on Methicillin-resistant Staphylococcus aureus (MRSA) with a MIC of 1 μg/mL. Antimicrobial agent-2 can effectively damage the membrane and lead to the leakage of protein, also can induce the generation of ROS. Antimicrobial agent-2 exhibits low toxicity, no obvious resistance and good bioavailability[1].

Name	Antimicrobial agent-2

Description	Antimicrobial agent-2 (compound V-a) is a broad-spectrum antimicrobial agent, possessing inhibitory activity against various Gram-positive and -negative bacteria. Antimicrobial agent-2 has excellent inhibitory effect on Methicillin-resistant Staphylococcus aureus (MRSA) with a MIC of 1 μg/mL. Antimicrobial agent-2 can effectively damage the membrane and lead to the leakage of protein, also can induce the generation of ROS. Antimicrobial agent-2 exhibits low toxicity, no obvious resistance and good bioavailability[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS
Target	MIC: 1 μg/mL (MRSA), 2 μg/mL (Enterococcus faecalis)[1]
References	[1]. Yang XC, et al. Coumarin thiazoles as unique structural skeleton of potential antimicrobial agents. Bioorg Chem. 2022;124:105855.

Molecular Formula	C₁₆H₁₄N₂O₄S
Molecular Weight	330.36