2091883-59-7

2091883-59-7 structure

2091883-59-7 structure

Name: Dyrk1A-IN-4
Chemical Name: Dyrk1A-IN-4
CAS Number: 2091883-59-7
Molecular Formula: C₁₄H₁₃F₃N₆
Molecular Weight: 322.29
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK DYRK
Create Date: 2022-06-26 14:50:33
Modify Date: 2024-01-11 17:06:08
Dyrk1A-IN-4 (compound 48) is a potent and orally active DYRK1A and DYRK2 inhibitor with IC50s of 2 nM and 6 nM, respectively. Dyrk1A-IN-4 has anticancer effects[1].

Name	Dyrk1A-IN-4

Description	Dyrk1A-IN-4 (compound 48) is a potent and orally active DYRK1A and DYRK2 inhibitor with IC50s of 2 nM and 6 nM, respectively. Dyrk1A-IN-4 has anticancer effects[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> DYRK
Target	DYRK1A:2 nM (IC50) DYRK2:6 nM (IC50)
References	[1]. Csaba Weber, et al. Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors. J Med Chem. 2021 May 27;64(10):6745-6764.

Molecular Formula	C₁₄H₁₃F₃N₆
Molecular Weight	322.29