2418549-33-2

2418549-33-2 structure

2418549-33-2 structure

Name: EGFR-IN-53
Chemical Name: EGFR-IN-53
CAS Number: 2418549-33-2
Molecular Formula: C₁₄H₁₃N₃O₂S
Molecular Weight: 287.34
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2022-07-19 11:27:27
Modify Date: 2024-01-03 15:18:32
EGFR-IN-53 (Compound 7) is a potent EGFR inhibitor with an IC50 of 8.264 µM. EGFR-IN-53 shows cytotoxic activity against cancer cell lines[1].

Name	EGFR-IN-53

Description	EGFR-IN-53 (Compound 7) is a potent EGFR inhibitor with an IC50 of 8.264 µM. EGFR-IN-53 shows cytotoxic activity against cancer cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR:8.264 μM (IC50)
References	[1]. Abbas SY, et al. Synthesis and anticancer activity of thiourea derivatives bearing a benzodioxole moiety with EGFR inhibitory activity, apoptosis assay and molecular docking study. Eur J Med Chem. 2020 Jul 15;198:112363.

Molecular Formula	C₁₄H₁₃N₃O₂S
Molecular Weight	287.34