2418549-30-9

2418549-30-9 structure

2418549-30-9 structure

Name: EGFR-IN-54
Chemical Name: EGFR-IN-54
CAS Number: 2418549-30-9
Molecular Formula: C₁₇H₁₄N₄O₄S₃
Molecular Weight: 434.51
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2022-08-06 15:07:36
Modify Date: 2024-01-08 17:20:19
EGFR-IN-54 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 1.623 µM. EGFR-IN-54 shows cytotoxic activity against cancer cell lines[1].

Name	EGFR-IN-54

Description	EGFR-IN-54 (Compound 3c) is a potent EGFR inhibitor with an IC50 of 1.623 µM. EGFR-IN-54 shows cytotoxic activity against cancer cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR:1.623 μM (IC50)
References	[1]. Abbas SY, et al. Synthesis and anticancer activity of thiourea derivatives bearing a benzodioxole moiety with EGFR inhibitory activity, apoptosis assay and molecular docking study. Eur J Med Chem. 2020 Jul 15;198:112363.

Molecular Formula	C₁₇H₁₄N₄O₄S₃
Molecular Weight	434.51