2428743-04-6

2428743-04-6 structure
2428743-04-6 structure
  • Name: FGFR3-IN-1
  • Chemical Name: FGFR3-IN-1
  • CAS Number: 2428743-04-6
  • Molecular Formula: C28H39N9O3S
  • Molecular Weight: 581.73
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
  • Create Date: 2022-07-02 02:26:59
  • Modify Date: 2024-01-09 09:34:27
  • FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor, with IC50s of 40 nM, 5.1 nM, and 12 nM for FGFR1, 2, and 3, respectively. FGFR3-IN-1 can be used for the research of bladder cancer[1].

Name FGFR3-IN-1
Description FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor, with IC50s of 40 nM, 5.1 nM, and 12 nM for FGFR1, 2, and 3, respectively. FGFR3-IN-1 can be used for the research of bladder cancer[1].
Related Catalog
Target

FGFR1:40 nM (IC50)

FGFR2:5.1 nM (IC50)

FGFR3:12 nM (IC50)

References

[1]. Kuriwaki I, et, al. Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2. Bioorg Med Chem. 2020 May 15;28(10):115453.

Molecular Formula C28H39N9O3S
Molecular Weight 581.73