2408599-78-8

2408599-78-8 structure

2408599-78-8 structure

Name: hCAII-IN-2
Chemical Name: hCAII-IN-2
CAS Number: 2408599-78-8
Molecular Formula: C₂₅H₁₈ClN₅O₄S
Molecular Weight: 519.96
Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
Create Date: 2022-06-25 21:22:52
Modify Date: 2024-01-09 21:36:50
hCAII-IN-2 (Compound 11f) is a cytosolic human carbonic anhydrase (hCA) inhibitor with Ki values of 261.4, 3.8, 19.6 and 45.2 nM against hCA I, hCA II, hCA IX and hCA XII, respectively[1].

Name	hCAII-IN-2

Description	hCAII-IN-2 (Compound 11f) is a cytosolic human carbonic anhydrase (hCA) inhibitor with Ki values of 261.4, 3.8, 19.6 and 45.2 nM against hCA I, hCA II, hCA IX and hCA XII, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	Ki: 3.8 nM (hCA II), 19.6 nM (hCA IX), 45.2 nM (hCA XII), 261.4 nM (hCA I)[1]
References	[1]. Khalil OM, et al. Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases. Eur J Med Chem. 2020 Feb 15;188:112021.

Molecular Formula	C₂₅H₁₈ClN₅O₄S
Molecular Weight	519.96