2416910-88-6

2416910-88-6 structure

Name: MAO-B-IN-9
Chemical Name: MAO-B-IN-9
CAS Number: 2416910-88-6
Molecular Formula: C₁₈H₂₄N₂O₂
Molecular Weight: 300.40
Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
Create Date: 2022-07-01 14:37:16
Modify Date: 2024-01-02 11:43:44
MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects[1].

Name	MAO-B-IN-9

Description	MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	MAO-B:0.178 ± 0. μM (IC50)
References	[1]. Košak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282.

Molecular Formula	C₁₈H₂₄N₂O₂
Molecular Weight	300.40