2088243-03-0

2088243-03-0 structure

Name: NS5A-IN-4
Chemical Name: NS5A-IN-4
CAS Number: 2088243-03-0
Molecular Formula: C₄₇H₄₈N₈O₆
Molecular Weight: 820.93
Catalog: Signaling Pathways Metabolic Enzyme/Protease HCV Protease
Create Date: 2022-06-30 13:52:00
Modify Date: 2024-01-14 15:33:06
NS5A-IN-4 (Compound 1.12) is an orally active pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with IC50 values of 1.2, 2296, 4.6, 362, 10.3 and 693 pM against gT1b, gT1a, gT2a, gT3a, gT4a and gT5a[1].

Name	NS5A-IN-4

Description	NS5A-IN-4 (Compound 1.12) is an orally active pan-genotypic hepatitis C virus (HCV) NS5A inhibitor with IC50 values of 1.2, 2296, 4.6, 362, 10.3 and 693 pM against gT1b, gT1a, gT2a, gT3a, gT4a and gT5a[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HCV Protease
Target	IC50: 1.2 pM (gT1b), 4.6 pM (gT2a), 10.3 pM (gT4a), 362 pM (gT3a), 693 pM (gT5a), 2296 pM (gT1a)[1]
References	[1]. Ivashchenko AA, et al. Synthesis, biological evaluation and in silico modeling of novel pan-genotypic NS5A inhibitors. Bioorg Med Chem. 2020 Oct 15;28(20):115716.

Molecular Formula	C₄₇H₄₈N₈O₆
Molecular Weight	820.93