326495-38-9

326495-38-9 structure

Name: 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74
Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74
CAS Number: 326495-38-9
Molecular Formula: C₄₄H₁₄D₇₄NO₈P
Molecular Weight: 864.60
Catalog: Research Areas Others
Create Date: 2022-08-21 13:23:02
Modify Date: 2022-08-21 13:23:02
1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly

Name	1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74

Description	1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].
References	[1]. Andrew D Miller. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811. [2]. Jayesh A Kulkarni, et al. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 21;11(45):21733-21739. [3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Molecular Formula	C₄₄H₁₄D₇₄NO₈P
Molecular Weight	864.60