2490538-26-4

2490538-26-4 structure

Name: Apoptotic agent-1
Chemical Name: Apoptotic agent-1
CAS Number: 2490538-26-4
Molecular Formula: C₁₂H₆ClN₅O₂S
Molecular Weight: 319.73
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-08-18 21:40:20
Modify Date: 2024-01-15 19:34:48
Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes[1].

Name	Apoptotic agent-1

Description	Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Apoptotic agent-1 (Compound 8a) shows antiproliferative activity with IC50 values of 53.3, 12.9 and > 100 µM against HepG2, MCF-7 and WI-38 cells, respectively[1].
References	[1]. Haffez H, et al. Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity. Bioorg Chem. 2020 Nov;104:104249.

Molecular Formula	C₁₂H₆ClN₅O₂S
Molecular Weight	319.73