93944-58-2

93944-58-2 structure

Name: α-Amylase-IN-3
Chemical Name: α-Amylase-IN-3
CAS Number: 93944-58-2
Molecular Formula: C₁₅H₉NO₄
Molecular Weight: 267.24
Catalog: Research Areas Cancer
Create Date: 2022-08-23 10:45:02
Modify Date: 2024-04-05 21:04:26
α-Amylase-IN-3 (Compound 4) is a none-competitive type of α-Amylase inhibitor with an IC50 value of 18.04 μM, which also has radical scavenging activities (DPPH and ABTS) with IC50 values of 16.04 μM (DPPH) and 16.99 μM (ABTS), respectively. α-Amylase-IN-3 has good protein–ligand interactions profile against α-Amylase. α-Amylase-IN-3 may have pharmacological activities such as anti-oxidative, anti-inflammatory inhibitory, which is helpful for the development of diabetes and oxidative stress associated disease[1].

Name	α-Amylase-IN-3

Description	α-Amylase-IN-3 (Compound 4) is a none-competitive type of α-Amylase inhibitor with an IC50 value of 18.04 μM, which also has radical scavenging activities (DPPH and ABTS) with IC50 values of 16.04 μM (DPPH) and 16.99 μM (ABTS), respectively. α-Amylase-IN-3 has good protein–ligand interactions profile against α-Amylase. α-Amylase-IN-3 may have pharmacological activities such as anti-oxidative, anti-inflammatory inhibitory, which is helpful for the development of diabetes and oxidative stress associated disease[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	IC50: 18.04 μM (α-Amylase), 16.04 μM (DPPH), 16.99 μM (ABTS)[1].
References	[1]. Na Li, et al. Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition. Bioorg Chem. 2020 Nov;104:104208.

Molecular Formula	C₁₅H₉NO₄
Molecular Weight	267.24