Shanghai Nianxing Industrial Co., Ltd
China
Product Name: FAK-IN-7
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

19948-85-7

19948-85-7 structure

19948-85-7 structure

Name: FAK-IN-7
Chemical Name: N-(5-(p-Tolyl)-1,3,4-thiadiazol-2-yl)benzamide
CAS Number: 19948-85-7
Molecular Formula: C₁₆H₁₃N₃OS
Molecular Weight: 295.36
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FAK
Create Date: 2022-09-13 06:27:47
Modify Date: 2024-01-10 03:43:11
FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 µM). FAK-IN-7 has good anti-proliferative activity and can be used in cancer research[1].

Name	N-(5-(p-Tolyl)-1,3,4-thiadiazol-2-yl)benzamide
Synonyms	MFCD00660411

Description	FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 µM). FAK-IN-7 has good anti-proliferative activity and can be used in cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FAK
Target	FAK:11.72 μM (IC50)
In Vitro	FAK-IN-7 (0-10 µM; 48 h) inhibits MCF-7 and B16-F10 cells proliferation[1]. Cell Proliferation Assay[1] Cell Line: MCF-7 and B16-F10 cells Concentration: 0-10 µM Incubation Time: 48 h Result: Exhibited anti-proliferative activity against MCF-7 and B16-F10 cells with IC50 values of 3.57 and 3.52 µM, respectively.
References	[1]. Yang XH, et al. Synthesis, biological evaluation, and molecular docking studies of 1,3,4-thiadiazol-2-amide derivatives as novel anticancer agents. Bioorg Med Chem. 2012 May 1;20(9):2789-95.

Molecular Formula	C₁₆H₁₃N₃OS
Molecular Weight	295.36