2785430-82-0
2785430-82-0 structure
- Name: ALK5-IN-26
- Chemical Name: ALK5-IN-26
- CAS Number: 2785430-82-0
- Molecular Formula: C24H25FN8
- Molecular Weight: 444.51
- Catalog: Research Areas Cancer
- Create Date: 2022-10-10 18:11:00
- Modify Date: 2024-04-07 05:45:28
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ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 with an IC50 value ≤10 nM. ALK5-IN-26 can be used for the research of cancer[1].
| Name | ALK5-IN-26 |
|---|
| Description | ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 with an IC50 value ≤10 nM. ALK5-IN-26 can be used for the research of cancer[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: ≤10 nM (ALK5)[1] |
| In Vitro | ALK5-IN-26 (0-1 μM; 24 h) inhibits ALK5 with an IC50 value ≤10 nM, and shows selectivity of ALK2 IC50/ALK5 IC50 of a ratio ＜100[1]. |
| References |
[1]. Franz B, et al. ALK-5 INHIBITORS AND USES THEREOF. WO/2022/126133 A1. 2022. |
| Molecular Formula | C24H25FN8 |
|---|---|
| Molecular Weight | 444.51 |