2304852-21-7

2304852-21-7 structure

Name: PAD-IN-2
Chemical Name: PAD-IN-2
CAS Number: 2304852-21-7
Molecular Formula: C₂₇H₂₈ClN₅O₂
Molecular Weight: 490.00
Catalog: Research Areas Cancer
Create Date: 2022-10-12 06:53:31
Modify Date: 2024-09-24 10:58:33
PAD-IN-2 is a potent pad4 inhibitor (IC50: <1 μM). PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and psoriasis[1].

Name	PAD-IN-2

Description	PAD-IN-2 is a potent pad4 inhibitor (IC50: <1 μM). PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and psoriasis[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Epigenetics >> Protein Arginine Deiminase
In Vitro	PAD-IN-2 (Example-57, 1 h) inhibits PAD4 activity with an IC50 value <1 μM (determined by ammonia release biochemical assay)[1].
References	[1]. Hallur, Gurulingappa, et al. Heterocyclic compounds as pad4 inhibitors. Patent WO2019058393 A1.

Molecular Formula	C₂₇H₂₈ClN₅O₂
Molecular Weight	490.00