2769753-48-0

2769753-48-0 structure

Name: RSS0680
Chemical Name: RSS0680
CAS Number: 2769753-48-0
Molecular Formula: C₅₂H₆₄N₁₀O₆S₃
Molecular Weight: 1021.32
Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
Create Date: 2022-10-08 12:11:05
Modify Date: 2024-01-11 17:32:52
RSS0680 (Example 22) is a bifunctional compound targeted protein degradation of kinases. RSS0680 degrades AAK1, CDK1, CDK16, CDK2, CDK4, CDK6, EIF2AK4, GAK, LATSl, LIMK2, MAPK6, MAPKAPK5, MARK2, MARK4, MKNK2, NEK9, RPS6KB1, SIK2, SNRK, STK17A, STK17B, STK35, and WEEl. RSS0680 can be used for research of disease or disorder mediated by aberrant kinase activity[1].

Name	RSS0680

Description	RSS0680 (Example 22) is a bifunctional compound targeted protein degradation of kinases. RSS0680 degrades AAK1, CDK1, CDK16, CDK2, CDK4, CDK6, EIF2AK4, GAK, LATSl, LIMK2, MAPK6, MAPKAPK5, MARK2, MARK4, MKNK2, NEK9, RPS6KB1, SIK2, SNRK, STK17A, STK17B, STK35, and WEEl. RSS0680 can be used for research of disease or disorder mediated by aberrant kinase activity[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Wee1 Research Areas >> Others Signaling Pathways >> Cell Cycle/DNA Damage >> LIM Kinase (LIMK) Signaling Pathways >> Cell Cycle/DNA Damage >> CDK Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Immunology/Inflammation >> Salt-inducible Kinase (SIK)
Target	CDK1 CDK2 CDK4 CDK6 SIK2 CDK16/Cyclin Y
References	[1]. Gray Nathanael S, et al. Bifunctional compounds for targeted protein degradation of kinases: World Intellectual Property Organization, WO2022093742[P]. 2022-05-05.

Molecular Formula	C₅₂H₆₄N₁₀O₆S₃
Molecular Weight	1021.32