2378427-68-8

2378427-68-8 structure

2378427-68-8 structure

Name: Gly-7-MAD-MDCPT
Chemical Name: Gly-7-MAD-MDCPT
CAS Number: 2378427-68-8
Molecular Formula: C₂₄H₂₂N₄O₇
Molecular Weight: 478.45
Catalog: Research Areas Cancer
Create Date: 2022-11-20 13:13:04
Modify Date: 2024-04-11 08:18:01
Gly-7-MAD-MDCPT (compound 4b) is an anticancer agent. Gly-7-MAD-MDCPT is a Camptothecin (HY-16560) compound, it shows cytotoxicity to various cancer cells with IC50 values of 10-1000 nM[1].

Name	Gly-7-MAD-MDCPT

Description	Gly-7-MAD-MDCPT (compound 4b) is an anticancer agent. Gly-7-MAD-MDCPT is a Camptothecin (HY-16560) compound, it shows cytotoxicity to various cancer cells with IC50 values of 10-1000 nM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Gly-7-MAD-MDCPT (0.1-1000 nM) shows cytotoxic potency to 786-0, BxPC3, HL-60 and SK-MEL-5 with IC50 values of 100-1000 nM[1]. Gly-7-MAD-MDCPT (0.1-1000 nM) shows cytotoxic potency to L540cy, MM.1R, M0LM13, Ramos, SK-MEL-5, SU-DHL-4 and U266 with IC50 values of 10-100 nM[1].
References	[1]. Jeffrey Scott, et al. Preparation of camptothecin peptide conjugates as antitumor agents. WO2019195665. 2019 10-10.

Molecular Formula	C₂₄H₂₂N₄O₇
Molecular Weight	478.45