2511247-29-1

2511247-29-1 structure

Name: HIF-2α-IN-7
Chemical Name: HIF-2α-IN-7
CAS Number: 2511247-29-1
Molecular Formula: C₁₈H₉F₆NO₂
Molecular Weight: 385.26
Catalog: Signaling Pathways Metabolic Enzyme/Protease HIF/HIF Prolyl-Hydroxylase
Create Date: 2022-11-21 12:56:39
Modify Date: 2024-01-10 15:50:25
HIF-2α-IN-7 is a hypoxia inducible factor 2α (HIF-2α) inhibitor. HIF-2α-IN-7 can inhibit HIF-2α with an EC50 value of 6nM. HIF-2α-IN-7 can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders[1].

Name	HIF-2α-IN-7

Description	HIF-2α-IN-7 is a hypoxia inducible factor 2α (HIF-2α) inhibitor. HIF-2α-IN-7 can inhibit HIF-2α with an EC50 value of 6nM. HIF-2α-IN-7 can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase Research Areas >> Metabolic Disease
Target	EC50: 6nM (HIF-2α)[1]
In Vitro	HIF-2α-IN-7 has inhibitory activity for HIF-2α with an EC50 value of 6nM[1].
References	[1]. Jiping Fu, et al. Tetrahydro-1h-cyclopenta[cd]indene derivatives as hypoxia inducible factor-2(alpha) inhibitors. Patent. WO2020214853A1.

Molecular Formula	C₁₈H₉F₆NO₂
Molecular Weight	385.26