153607-26-2

153607-26-2 structure

Name: Neurokinin Receptor (393-407), rat
Chemical Name: Neurokinin Receptor (393-407), rat
CAS Number: 153607-26-2
Molecular Formula: C₇₂H₁₁₃N₁₇O₂₆S₂
Molecular Weight: 1696.90
Catalog: Signaling Pathways GPCR/G Protein Neurokinin Receptor
Create Date: 2023-01-19 05:29:59
Modify Date: 2023-01-19 05:29:59
Neurokinin Receptor (393-407), rat (SPR393–407) is a rat neurokinin 1 receptor (NK1R) fragment. NK1R is rapidly internalized by endocytosis and recycled to the plasma membrane when binding to substance P (SP). Neurokinin Receptor (393-407), rat can be used in the research of neurogenic inflammation[1][2].

Name	Neurokinin Receptor (393-407), rat

Description	Neurokinin Receptor (393-407), rat (SPR393–407) is a rat neurokinin 1 receptor (NK1R) fragment. NK1R is rapidly internalized by endocytosis and recycled to the plasma membrane when binding to substance P (SP). Neurokinin Receptor (393-407), rat can be used in the research of neurogenic inflammation[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
Target	NK1
In Vitro	Neurokinin Receptor (393-407), rat (10 pM) 抑制 50% 的 125I-SPR393-407 与抗血清结合。
References	[1]. Nathan JD, et al. Capsaicin vanilloid receptor-1 mediates substance P release in experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2001 Nov;281(5):G1322-8. [2]. Vigna SR, et al. Characterization of antibodies to the rat substance P (NK-1) receptor and to a chimeric substance P receptor expressed in mammalian cells. J Neurosci. 1994 Feb;14(2):834-45.

Molecular Formula	C₇₂H₁₁₃N₁₇O₂₆S₂
Molecular Weight	1696.90