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1375752-77-4

1375752-77-4 structure
1375752-77-4 structure
  • Name: (S,S)-BMS-984923
  • Chemical Name: (S,S)-BMS-984923
  • CAS Number: 1375752-77-4
  • Molecular Formula: C22H15ClN2O2
  • Molecular Weight: 374.82
  • Catalog: Signaling Pathways GPCR/G Protein mGluR
  • Create Date: 2023-01-17 13:12:02
  • Modify Date: 2024-09-10 08:22:05
  • (S,S)-BMS-984923 is a less active (S,S)-enantiomer of BMS-984923. (S,S)-BMS-984923 shows an EC50 >1μM for mGluR5 receptor[1]. BMS-984923 is a potent mGluR5 silent allosteric modulator[2].
Name (S,S)-BMS-984923
Description (S,S)-BMS-984923 is a less active (S,S)-enantiomer of BMS-984923. (S,S)-BMS-984923 shows an EC50 >1μM for mGluR5 receptor[1]. BMS-984923 is a potent mGluR5 silent allosteric modulator[2].
Related Catalog
References

[1]. Andrew P. Degnan, et al. Oxazolidinones as modulators of mglur5. WO2012064603A1.

[2]. Laura T Haas, et al. Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes. Cell Rep. 2017 Jul 5;20(1):76-88.  

Molecular Formula C22H15ClN2O2
Molecular Weight 374.82

Chemsrc provides CAS#:1375752-77-4 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 1375752-77-4 | Chemsrc address: https://www.chemsrc.com/en/baike/1727502.html

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