541547-35-7

541547-35-7 structure

Name: Agatolimod sodium
Chemical Name: Agatolimod sodium
CAS Number: 541547-35-7
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
Create Date: 2023-04-29 11:21:04
Modify Date: 2024-04-05 17:48:02
Agatolimod sodium (ODN 7909) is a class B CpG ODN and is a TLR9 agonist. Agatolimod sodium can be used as vaccine adjuvant. Agatolimod sodium can be used for the research of cancer. Sequence: 5’-TCGTCGTTTTGTCGTTTTGTCGTT-3’[1][2].

Name	Agatolimod sodium

Description	Agatolimod sodium (ODN 7909) is a class B CpG ODN and is a TLR9 agonist. Agatolimod sodium can be used as vaccine adjuvant. Agatolimod sodium can be used for the research of cancer. Sequence: 5’-TCGTCGTTTTGTCGTTTTGTCGTT-3’[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Cancer
Target	TLR9
In Vitro	Agatolimod sodium (ODN 7909) (10 μg/mL; 24 and 48 h) increases radiation sensitivity of radiation-resistant human lung adenocarcinoma cell line by overexpression of TLR9[1].
References	[1]. Yan L, et al. CpG-ODN 7909 increases radiation sensitivity of radiation-resistant human lung adenocarcinoma cell line by overexpression of Toll-like receptor 9. Cancer Biother Radiopharm. 2013 Sep;28(7):559-64. [2]. Cooper CL, et al. Safety and immunogenicity of CPG 7909 injection as an adjuvant to Fluarix influenza vaccine. Vaccine. 2004 Aug 13;22(23-24):3136-43.

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