2760481-53-4

2760481-53-4 structure

Name: TNG908
Chemical Name: TNG908
CAS Number: 2760481-53-4
Molecular Formula: C₂₁H₂₃N₅O₂S
Molecular Weight: 409.50
Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
Create Date: 2023-04-10 08:50:37
Modify Date: 2024-01-13 19:09:23
TNG908 is a MTAP-cooperative PRMT5 inhibitor that can pass through the blood-brain barrier. TNG908 is 15 times more selective for MTAP null cell lines than MTAPWT cell lines, and can be used in cancer research[1].

Name	TNG908

Description	TNG908 is a MTAP-cooperative PRMT5 inhibitor that can pass through the blood-brain barrier. TNG908 is 15 times more selective for MTAP null cell lines than MTAPWT cell lines, and can be used in cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
References	[1]. K. Briggs, et al. TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor for the treatment of MTAP-deleted cancer.MOLECULAR TARGETED AGENTS 2\| VOLUME 174, SUPPLEMENT 1, S84, OCTOBER 2022.

Molecular Formula	C₂₁H₂₃N₅O₂S
Molecular Weight	409.50