TNG908

Modify Date: 2024-01-13 19:09:23

TNG908 structure	Common Name	TNG908
	CAS Number	2760481-53-4	Molecular Weight	409.50
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₃N₅O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TNG908

TNG908 is a MTAP-cooperative PRMT5 inhibitor that can pass through the blood-brain barrier. TNG908 is 15 times more selective for MTAP null cell lines than MTAPWT cell lines, and can be used in cancer research[1].

Name	TNG908

Description	TNG908 is a MTAP-cooperative PRMT5 inhibitor that can pass through the blood-brain barrier. TNG908 is 15 times more selective for MTAP null cell lines than MTAPWT cell lines, and can be used in cancer research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
References	[1]. K. Briggs, et al. TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor for the treatment of MTAP-deleted cancer.MOLECULAR TARGETED AGENTS 2\| VOLUME 174, SUPPLEMENT 1, S84, OCTOBER 2022.