2470972-18-8

2470972-18-8 structure

Name: Dihydro-5-azacytidine acetate
Chemical Name: Dihydro-5-azacytidine acetate
CAS Number: 2470972-18-8
Molecular Formula: C₁₀H₁₈N₄O₇
Molecular Weight: 306.27
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2023-09-20 23:39:33
Modify Date: 2024-01-11 19:29:08
Dihydro-5-azacytidine acetate (DHAC), the nucleoside analog, is incorporated into DNA and inhibits DNA methylation. Dihydro-5-azacytidine acetate has an antitumor activity[1][2].

Name	Dihydro-5-azacytidine acetate

Description	Dihydro-5-azacytidine acetate (DHAC), the nucleoside analog, is incorporated into DNA and inhibits DNA methylation. Dihydro-5-azacytidine acetate has an antitumor activity[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Signaling Pathways >> Epigenetics >> DNA Methyltransferase
References	[1]. Robert A Kratzke, et al. Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a: results of cancer and leukemia group B 159904. J Thorac Oncol. 2008 Apr;3(4):417-21. [2]. W C Powell, et al. Biochemical pharmacology of 5,6-dihydro-5-azacytidine (DHAC) and DNA hypomethylation in tumor (L1210)-bearing mice. Cancer Chemother Pharmacol. 1988;21(2):117-21.

Molecular Formula	C₁₀H₁₈N₄O₇
Molecular Weight	306.27