2889356-55-0

2889356-55-0 structure

Name: Phosphatase-IN-1
Chemical Name: Phosphatase-IN-1
CAS Number: 2889356-55-0
Molecular Formula: C₁₆H₁₆Cl₂FNO₂
Molecular Weight: 344.21
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2023-11-26 19:38:47
Modify Date: 2024-01-12 07:47:57
Phosphatase-IN-1 (compound II-8), a propranolol (HY-B0573B) derivative, is a phosphatidate phosphatase (Pah) inhibitor. Phosphatase-IN-1 can binds to MoPah1, with an affinity constant of 19.8 μM. Phosphatase-IN-1 inhibits growth of plant pathogens and shows anti-fungal ability. Phosphatase-IN-1 is not toxic to rice seedlings and wheat heads[1].

Name	Phosphatase-IN-1

Description	Phosphatase-IN-1 (compound II-8), a propranolol (HY-B0573B) derivative, is a phosphatidate phosphatase (Pah) inhibitor. Phosphatase-IN-1 can binds to MoPah1, with an affinity constant of 19.8 μM. Phosphatase-IN-1 inhibits growth of plant pathogens and shows anti-fungal ability. Phosphatase-IN-1 is not toxic to rice seedlings and wheat heads[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Zhao J, et al. Identification of propranolol and derivatives that are chemical inhibitors of phosphatidate phosphatase as potential broad-spectrum fungicides. Plant Commun. 2023 Aug 30:100679.

Molecular Formula	C₁₆H₁₆Cl₂FNO₂
Molecular Weight	344.21