4896-75-7
4896-75-7 structure
- Name: Glycine-d2
- Chemical Name: 2-amino-2,2-dideuterioacetic acid
- CAS Number: 4896-75-7
- Molecular Formula: C2H3D2NO2
- Molecular Weight: 77.079
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
- Create Date: 2018-04-03 08:00:00
- Modify Date: 2024-01-02 23:20:48
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Glycine-d2 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
| Name | 2-amino-2,2-dideuterioacetic acid |
|---|---|
| Synonyms |
2,2-2H2>glycine-2,2-d2
Glycine-2,2-d2 <2-2H2>glycine (2,2-H)Glycine MFCD00075077 Glycine-d2 Glycine-2,2-d |
| Description | Glycine-d2 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 240.9±23.0 °C at 760 mmHg |
| Melting Point | 240ºC (dec.)(lit.) |
| Molecular Formula | C2H3D2NO2 |
| Molecular Weight | 77.079 |
| Flash Point | 99.5±22.6 °C |
| Exact Mass | 77.044579 |
| PSA | 63.32000 |
| LogP | -1.03 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.461 |
| Storage condition | 2-8°C |
| RIDADR | NONH for all modes of transport |
|---|
|
~97%
4896-75-7 |
| Literature: Mitulovi, Goran; Laemmerhofer, Michael; Maier; Lindner, Wolfgang Journal of Labelled Compounds and Radiopharmaceuticals, 2000 , vol. 43, # 5 p. 449 - 461 |
|
~%
4896-75-7 |
| Literature: Hellerstein, Marc K. Patent: US2003/228259 A1, 2003 ; Location in patent: Page 4 ; |
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~%
4896-75-7 |
| Literature: Hellerstein, Marc K. Patent: US2003/228259 A1, 2003 ; Location in patent: Page 4 ; |
| Precursor 2 | |
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| DownStream 3 | |
