97743-99-2

97743-99-2 structure

Name: Desmethylcitalopram (hydrochloride)
Chemical Name: 1-(4-fluorophenyl)-1-[3-(methylamino)propyl]-3H-2-benzofuran-5-carbonitrile,hydrochloride
CAS Number: 97743-99-2
Molecular Formula: C₁₉H₂₀ClFN₂O
Molecular Weight: 346.82600
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
Create Date: 2016-07-04 06:28:53
Modify Date: 2024-01-19 12:16:30
Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC50s of 39.5 and 53.5 μM[1].

Name	1-(4-fluorophenyl)-1-[3-(methylamino)propyl]-3H-2-benzofuran-5-carbonitrile,hydrochloride
Synonyms	UNII-461OE8B9GL rac Desmethyl Citalopram Hydrochloride

Description	Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC50s of 39.5 and 53.5 μM[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Neurological Disease
References	[1]. von Moltke LL, et aI. Citalopram and desmethylcitalopram in vitro: human cytochromes mediating transformation, and cytochrome inhibitory effects. Biol Psychiatry. 1999 Sep 15;46(6):839-49.