1796557-72-6

1796557-72-6 structure

1796557-72-6 structure

Name: HSP70/SIRT2-IN-2
Chemical Name: HSP70/SIRT2-IN-2
CAS Number: 1796557-72-6
Molecular Formula: C₁₇H₁₃N₃S₃
Molecular Weight: 355.50
Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
Create Date: 2024-01-11 16:45:04
Modify Date: 2024-01-11 16:45:04
HSP70/SIRT2-IN-2 (Compounds 1a) is a dual inhibitor for SIRT2 and HSP70, with IC50 of 45.1±5.0 μM for SIRT2. HSP70/SIRT2-IN-2 has antitumor activity[1].

Name	HSP70/SIRT2-IN-2

Description	HSP70/SIRT2-IN-2 (Compounds 1a) is a dual inhibitor for SIRT2 and HSP70, with IC50 of 45.1±5.0 μM for SIRT2. HSP70/SIRT2-IN-2 has antitumor activity[1].
Related Catalog	Signaling Pathways >> Epigenetics >> Sirtuin Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
References	[1]. Elena Abbotto, et al. Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays. Pharmaceuticals (Basel). 2023 Sep 18;16(9):1316.

Molecular Formula	C₁₇H₁₃N₃S₃
Molecular Weight	355.50