866889-02-3
866889-02-3 structure
- Name: HS-PEG8-CH2CH2COOH
- Chemical Name: 3-[2-[2-[2-[2-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
- CAS Number: 866889-02-3
- Molecular Formula: C19H38O10S
- Molecular Weight: 458.56400
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-06-28 10:26:31
- Modify Date: 2024-01-13 17:16:46
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Thiol-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-[2-[2-[2-[2-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
|---|---|
| Synonyms |
AmbotzPEG1120
PEG thiol acid 4,7,10,13,16,19,22,25-Octaoxaheptacosanoicacid,27-mercapto |
| Description | Thiol-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C19H38O10S |
|---|---|
| Molecular Weight | 458.56400 |
| Exact Mass | 458.21900 |
| PSA | 149.94000 |
| LogP | 0.52370 |
| Hazard Codes | Xi |
|---|